The impact of somatic SMAD4 mutations in colorectal liver metastases
نویسندگان
چکیده
منابع مشابه
Impact of liver-directed therapy in colorectal cancer liver metastases.
BACKGROUND There is a paucity of data on the current management and outcomes of liver-directed therapy (LDT) in older patients presenting with stage IV colorectal cancer (CRC). The aim of the study was to evaluate treatment patterns and outcomes in use of LDT in the setting of improved chemotherapy. METHODS We used Cancer Registry and linked Medicare claims to identify patients aged ≥66 y und...
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acknowledge the importance of e-commerce to their countries and to survival of their businesses and in creating and encouraging an atmosphere for the wide adoption and success of e-commerce in the long term. the investment for implementing e-commerce in the public sector is one of the areas which is focused in government‘s action plan for cross-disciplinary it development and e-readiness in go...
Colorectal liver metastases.
BACKGROUND Despite major advances in therapies for liver metastases, colorectal cancer remains one of the commonest causes of cancer-related deaths in the UK. SOURCES OF DATA The international literature on the management of colorectal liver metastases (CLM) was reviewed. AREAS OF AGREEMENT Due to a combination of highly active systemic agents and low perioperative mortality achieved by hig...
متن کاملColorectal liver metastases
Each year in the UK, between 1214 000 people develop liver metastases from colorectal cancer. These metastases will contribute to the death ofthe patient in about 80% ofcases. Treatments aimed at these tumours are best administered when the tumour is small. Current investigative methods allow tumours as small as 0.5 mm to be detected, and should be offered to all colorectal cancer patients at r...
متن کاملColorectal Liver Metastases
The diagnosis and management of CRLM is complex and requires a multidisciplinary team approach for optimal outcomes. Over the past several decades, the 5-year survival following resection of CRLM has increased and the criteria for resection have broadened substantially. Even patients with multiple, bilateral CRLM, previously thought unresectable, may now be candidates for resection. Two-stage h...
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ژورنال
عنوان ژورنال: Chinese Clinical Oncology
سال: 2019
ISSN: 2304-3865,2304-3873
DOI: 10.21037/cco.2019.08.04